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August edition is now available

Integrated disease management programmes for chronic obstructive pulmonary disease

A Cochrane review shows that multicomponent and multidisciplinary integrated disease management programmes for people with chronic obstructive pulmonary disease are associated with better quality of life and exercise capacity and fewer hospital admissions for exacerbations up to 12 months.

Agomelatine for depression
A meta-analysis suggests that agomelatine is as effective as other antidepressants and causes slightly fewer discontinuations due to adverse effects. However, the relative incidence of individual adverse effects was not studied.

Psychotherapy for anorexia nervosa
A randomised controlled trial in Germany reports that focal psychodynamic therapy and enhanced cognitive behavioural therapy are no better than usual psychotherapy for weight gain in women with anorexia nervosa.

Muscle training for pelvic organ prolapse
A randomised controlled trial suggests that one-to-one pelvic floor muscle training may reduce the symptoms of pelvic organ prolapse.

Adverse events after quadrivalent human papillomavirus vaccination
A population cohort study in Denmark and Sweden finds no consistent evidence for causal associations between the quadrivalent human papillomavirus vaccine and a wide range of venous, autoimmune and neurological adverse outcomes.

Evidence Updates
NICE has recently published an Evidence Update on:

Antibiotics for early-onset neonatal infection